Drug Discovery Research Screening Libraries
Abcam GANT58, Hh signaling inhibitor, 10MG
MW 392.48 g/mol, Purity >99%. Inhibits Hh signaling downstream of smo and sufu. IC₅₀ = 5 μM for glioma associated oncogene expression in MEFs.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Lysophosphatidic acid sodium salt, autophagy inhibitor, 5MG
MW 458.5 g/mol, Purity >98%. Endogenous agonist of the Lysophosphatidic acid (LPA) receptors. Induces cellular functions such as cell proliferation and migration, and ICAM-1, IL-8 and MCP-1 expression. Inhibits autophagy in cells under starvation conditions by inhibiting autophagosome formation.
The product is subject to the following: Abcam Restricted Use Statement
Abcam GANT58, Hh signaling inhibitor, 50MG
MW 392.48 g/mol, Purity >99%. Inhibits Hh signaling downstream of smo and sufu. IC₅₀ = 5 μM for glioma associated oncogene expression in MEFs.
The product is subject to the following: Abcam Restricted Use Statement
Bioss KD-Validated Ubiquitination Fa
Ubiquitination Factor E4B Primary Antibody Unconjugated Public Immunogen Range 747-794/794 Host Species Rabbit Target Species Human Mouse Rat Clonality Monoclonal Applications WB FCM Concentration Lot dependent Size 50 ul Storage Buffer Supplied in PBS (pH 7 4) containing 50% glycerol and 0 02% sodium azide
Apexbio Technology LLC DiscoveryProbe™ MAPK Inhibitor Library, 250uL/well(10 mM solution), 96 Well Racks With Screw Cap
A unique collection of 117 MAPK inhibitors for MAPK signaling pathway research. Other sizes are available. Please inqury us for quote.
Apexbio Technology LLC DiscoveryProbe™ NF-B Signaling Library, 100uL/well(10 mM solution), 96 Well Racks With Screw Cap
A unique collection of 73 NF-B inhibitors for NF-B signaling pathway research. Other sizes are available. Please inqury us for quote.
Apexbio Technology LLC DiscoveryProbe™ Anti-diabetic Compound Library, 250uL/well(10 mM solution),96 Well Racks With Screw Cap
A unique collection of 110 anti-diabetic small molecule compounds for diabetes research. Other sizes are available. Please inqury us for quote.
AdipoGen Hexamethonium bromide
Chemical. CAS 55-97-0. Formula C12H30Br2N2. MW BD9837. Hexamethonium bromide is a peripherally-acting nondepolarizing neuromuscular blocking agent that acts as a non-competitive antagonist of nicotinic acetylcholine receptors nAChRs. Formulations containing hexamethonium were previously used in the treatment of hypertension. Induces apoptosis and inhibits the stimulatory effect of nicotine on endothelial cell DNA synthesis and proliferation.
AdipoGen Hexamethonium bromide
Chemical. CAS 55-97-0. Formula C12H30Br2N2. MW BD9837. Hexamethonium bromide is a peripherally-acting nondepolarizing neuromuscular blocking agent that acts as a non-competitive antagonist of nicotinic acetylcholine receptors nAChRs. Formulations containing hexamethonium were previously used in the treatment of hypertension. Induces apoptosis and inhibits the stimulatory effect of nicotine on endothelial cell DNA synthesis and proliferation.
AdipoGen Nigericin sodium salt
Chemical. CAS 28643-80-3. Formula C40H67NaO11. MW 746.94. Nigericin is an antibiotic, used as a high affinity ionophore for monovalent cations such as H, K, Na, Pb2. It shows antibacterial Gram-positive, antifungal, antitumor and antiviral activity and disrupts membrane potential of mitochondria. It sprimary use is as a NLRP3 activator in inflammasome research.
Apexbio Technology LLC DiscoveryProbe™ Bioactive Compound Library Plus, 100uL/well(10 mM solution), 96 Well Racks With Screw Cap
DiscoveryProbe™ Bioactive Compound Library Plus is a ready-to-use chemical library used for drug discovery, lab drug screening, drug target identification, and other pharmaceutical-related applications. It is available for high-throughput screening (HTS) and high-content screening (HCS). It consists of over 4400 small molecules with validated biological and pharmacological activities. Other sizes are also available. Please inqury us for quote.
Apexbio Technology LLC DiscoveryProbe™ Ion Channel Compound Library, 250uL/well(10 mM solution), 96 Well Racks With Screw Cap
A unique collection of 199 ion channel-related compounds for high throughput screening (HTS) and high content screening (HCS). Other sizes are available. Please inqury us for quote.
Apexbio Technology LLC DiscoveryProbe™ FDA-approved Library, 100uL/well(10 mM solution), 96 Well Deep Well Plate
DiscoveryProbe™ FDA-approved drug library includes 1971 FDA approved drugs for high throughput screening (HTS) and high content screening (HCS). It can be used to find new targets for old drugs. The bioactivity and safety of these drugs were confirmed by clinical trials. As they are all FDA-approved drugs, the drugs screened can be used for clinical testing directly. Other sizes are available, contact us for quote.
AdipoGen Rubpy2phen-5-NH2PF62
Chemical. CAS 84537-86-0. Formula C32H25N7Ru . 2PF6. MW 898.59. Rubpy2phen-5-NH2PF62 is a fluorescent metal-ligand complex probe. It shows high brightness and large Stokes Shift. Spectral Data lambdaex=458nm lambdaem=612nm in 0.1 M Tris pH 7.0. It has been used as starting material for synthesis of long-lifetime luminescent Ru complexes and in the preparation of amino-rutheniumii complex functionalized gold nanoparticles, which could be used as probe in biosensors and bioassays. Rubpy2phen-5-NH2PF62 is has also been used to synthesize fluorescent silica nanoparticles with ultrabrightness and photostability by encapsulating it into silica nanoparticles by a modified reversed microemulsion method. Could be used for the determination of nucleotide base sequences.